A multicentric study compared the efficacy of Naturoplex® tablets with antibiotics Norfloxacin and Ampicillin.
A multicentric study involved 2581 patients, of both sexes with different urinary tract infections such as: acute kidney inflammation, chronic progressive inflammations, bladder inflammations, prostate inflammations, and urinary tract inflammations. Patients were divided into two groups. One, containing 1798 patients received Naturoplex®, and a control group numbering 783 patients (positive control) received Norfloxacin or Ampicillin, two of the most commonly prescribed antibiotics for urinary tract infections’ treatment. Products were received during 15 days in recommended doses. After completing the therapy, patients were monitored for 6 more months to determine the percentage of infection returning (recidivism.
Overall therapeutically positive effect was achieved in 95.05% patients receiving Naturoplex® and in 84.04% of patients receiving antibiotics. Recidivism was monitored during the next 6 months in 213 patients that were treated with Naturoplex® and 87 patients that were treated with one of the antibiotics. During this time period, recidivism in the first group was seen in 4.23% of patients, and 43.59% of patients from the control group. In comments from the authors of this study, it has been recommended that therapy of acute inflammations with Naturoplex be extended by 5 days, while in chronic inflammations therapy should be extended by 10 more days to prevent reoccurrence of infections (recidivism of illness). In this, as well as other clinical studies done on Naturoplex® did not show any side effects.
|UTI||2581||Positive therapy effect|
|I group, Therapy: Naturoplex||1798||95.05%|
|II group, Therapy: Norfloxacin||783||84.04%|
|UTI||2581||Recidivism (illness reoccurring)|
|I group, Therapy: Naturoplex||1798||4.23%|
|II group, Therapy: Norfloxacin||783||43.59%|